I used to have a desktop pc but now just use a laptop: Dell XPS 17 9700. This has:
CPU: Intel Core i7 10750H.
RAM: 64GB DDR4/2666.
Display: 17 inch 4K OLED @ 60Hz.
GPU: GeForce GTX 1650.
Storage: 2 GB Samsung NVMe SSD.
Ports: 4 USB-cC
I add a Samsung T5 external 2Gb ssd and a Wacom Medium Intuos Pro digital painting tablet (pth-660) with thick and thin pens. I find the medium size much better for drawing and painting - it makes drawing curves and straight lines easier because you use the arm and not just the wrist. I calibrate my laptop's 4k display with an xRite i1 Display Pro. I use a Logitech MX Master 3S Wireless mouse.
I use Photoshop and Corel Painter in equal measure. Other software I use is: Topaz Simplify and Restyle, DXO Viewpoint 3 and DFT Photocopy 2.